Thymidine kinase 1 (TK1) phosphorylates Storage Bed thymidine nucleosides to generate thymidine monophosphate.This reaction belongs to the pyrimidine salvage route that is phylogenetically conserved.In the model plant Arabidopsis thaliana, TK activity contributes to maintain nuclear and organellar genome integrity by providing deoxythymidine-tripho
Reactivating the extracellular matrix synthesis of sulfated glycosaminoglycans and proteoglycans to improve the human skin aspect and its mechanical properties
Hanane Chajra,1 Daniel Auriol,1 Francine Joly,2 Aurélie Pagnon,3 Magda Rodrigues,4 Sophie Allart,4 Gérard Redziniak,5 Fabrice Lefevre1 1Libragen, Induchem (Givaudan Active Beauty), Toulouse, 2Sephra Pharma, Puteaux, 3Novotec, Bron, 4Centre de Physiopathologie de Toulouse-Purpan, Toulouse, 5Cosmetic Inventions, Antony, France Backgroun
The intersection of food insecure populations in the Midwest U.S. and rates of chronic health conditions
Abstract Background Food insecurity is the state of having insufficient access to adequate food in order to maintain a healthy lifestyle due to limited economic resources.This study expands upon the annual survey conducted by the USDA ERS, while providing evidence that additional factors, notably, medical or health-related issues play vital roles i
Similarly Lethal Strains of Extraintestinal Pathogenic Escherichia coli Trigger Markedly Diverse Host Responses in a Zebrafish Model of Sepsis
ABSTRACT In individuals with sepsis, the infecting microbes are commonly viewed as generic inducers of inflammation while the host background is considered the primary variable affecting disease progression and outcome.To study the effects of bacterial strain differences on the maladaptive immune responses that are induced during sepsis, we employe
The rise and fall of cryptocurrencies: defining the economic and social values of blockchain technologies, assessing the opportunities, and defining the financial and cybersecurity risks of the Metaverse
Abstract This study examines blockchain technologies and their pivotal role in the evolving Metaverse, shedding light on topics such as how to invest in copyright, the mechanics behind copyright mining, and strategies to effectively buy and trade cryptocurrencies.While it contextualises the common queries of "why is copyright crashing?" and "why is